The textbook analyzes problems facing organizations and employees in the 21st century. In addition to the fundamentals of organizational behavior, it examines the current state of rapidly developing organizations that face uncertainty, constant change and the impact of high technologies. It presents various models, technologies and tools of business changes aimed at radical organizational transformations. The manual contains a brief overview of the theoretical material, practical assignments and examples of case studies with a breakdown by topic, materials for students’ independent work and homework, recommendations for writing term and diploma papers. The manual is intended for students of economic specialties.